The assignment should consist of one review article on the latest Literature

The assignment should consist of one article on the latest developments on the pathophysiology of a named disease. (Drug treatments for Alzherimers Disease) - Literature review Example Developing management plans for the disease has been a daunting task that is still being researched on. It has been established that the disease cannot be cured but it can be managed to prevent continued degeneration. Anticholinergic drugs were used at that time with the use levodopa being adopted later. This was done after the discovery of dopaminergic deficits in the pathophysiology of the disease. The disease is quite common and affects the nervous system with patients having symptoms such as tremor, slowness in movement, rigidity and instability. It’s a neurodegenerative disorder and research shows that it affects about one per cent of the population from the age of seventy (Savitt, Dawson & Ted, 2006). The greatest development in the treatment of PD was the development of ways to correct dopamine deficiency which is greatly associated with the disease. Halting disease progression has been the greatest nightmare in science and medicine as the medical therapy used is just used to provide temporary relief and not a long term solution for the disease. The need, to do this research on Parkinson’s disease, was necessitated by the fact it is the second most common neurodegenerative disorder (Barbara & Lang, 2014). There are various factors associated with the onset of the disease with various genetic and environmental factors being thought to have an interaction that results to the disease (Bekris, Mata & Zabetian, 2010). Familial Parkinsonism which is detected when patients show symptoms such as rigidity, tremor and slowness in movement has been shown to be caused by mutation in six genes which include SNCA, ATP13A2, PINK1, DJ1, PRKN and LRRK2 (Bekris, Mata & Zabetian, 2010). Other factors, which have been seen as predisposing factors or leading to the disease, include variation in the MAPT, SNCA, and LRRK2. Putting the individual at a vulnerable position makes them to show the symptoms

Utopia Essay Example | Topics and Well Written Essays - 500 words

Utopia - Essay Example Houyhnhnm Land and El Dorado differ considerably in their environment. Houyhnhnm Land is an island, accessible only by sea. El Dorado is land-locked, â€Å"bounded by inaccessible mountains† (Voltaire, 76). The former has a largely natural pastoral environment with â€Å"plenty of grass, and several fields of oats† (Swift, 6). On the other hand, El Dorado is characterized by a more contrived, landscaped beauty. The beaten roads of Houyhnhnm are in contrast to the covered roads of El Dorado, on which the pebbles and sand are gold and precious stones. The public buildings and houses in El Dorado are built on a palatial scale, and are adorned with all manner of precious material. Even the â€Å"very plain house† (Voltaire, 78) of the retired courtier is ornamented in gold and silver. On the other hand, in Houyhnhnm Land, the â€Å"buildings, although very rude and simple, are not inconvenient, but well contrived to defend them from all injuries of cold and heatâ₠¬  (Swift, 12). In all aspects, Houyhnhnm Land is the epitome of simplicity, while El Dorado is filled with material wealth. The inhabitants of the two lands stand in marked opposition to each other. The Houyhnhnms are highly refined, intelligent horses, whose â€Å"grand maxim is, to cultivate reason, and to be wholly governed by it† (Swift,  9). In contrast to these noble horses, Houyhnhnm Land is also inhabited by the savage-like Yahoos, who are completely ruled by avarice and sensual depravity. The citizens of El Dorado are of one kind only: humans who have no passion for the gold and jewels which abound in their land. Peruvian is the language of El Dorado, while the Houyhnhnms and Yahoos have their distinct speeches. There is no religion in Houyhnhnm Land while the people of El Dorado offer thanksgiving to a single God, without the trappings of formal religious institutions. El Dorado has a â€Å"palace of sciences, --- filled with instruments